THE volume under review is the fourth edition, revised and enlarged, of a “Biological Monograph” first published in 1925. As the editors point out, “Conspicuous progress is now being seen in the field ...

Previous surveys, in 1978 to 1979 and in 1989, of Original Articles published in the New England Journal of Medicine revealed increasing sophistication of statistical methods over time. 1,2 The use of ...

A variety of statistical tools can detect potential breaches in the integrity of elections. These techniques draw on tools from many fields, including pure mathematics, statistics, and machine ...

Precision oncology exploits genomic, immunologic, and other biomarkers to drive discovery, drug development, and clinical care for patients with cancer. Precision oncology helps devise individualized ...

Statistical methods now being used in adaptive biomarker-driven clinical trials are reviewed. Some previous paradigms for clinical trial design can limit the development of more effective methods on ...