Researchers found a commercial deworming tablet released only 10% of its drug content in dissolution testing, prompting investigation of new formulations designed to improve drug release and extend ...
In the manufacture of solid dosage forms, the rate at which the active pharmaceutical ingredient (API) is dissolved into solvents simulating the digestive tract fluids is determined with dissolution ...
Over 141,000 bottles of cholesterol medication have been recalled due to “failed dissolution specifications,” suggesting that the drugs did not pass a solubility test, or failed to dissolve at a ...