Since the effects of gender-affirming therapy on fertility are unknown, multiple medical societies endorse the preservation of fertility in persons who identify as transgender. 1-3 In transgender male ...

Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

In a new study published in the journal Nature, researchers in Japan report that activating just eight genes for producing gene-controlling proteins is enough to convert mouse stem cells directly into ...

Researchers have found that a carefully orchestrated act of X-chromosome 'yoyo' predicts the successful and efficient development of mammalian egg cells. The findings could pave the way for generating ...

This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

Females are born with a finite number of eggs that are steadily depleted throughout their lifetime. This reserve of eggs is selected from a much larger pool of millions of precursor cells, or oocytes, ...

Oocyte cryopreservation is a suitable fertility preservation option for women who are not partnered, have ethical objections to cryopreserving embryos or wish to have complete reproductive autonomy.

Human oocytes can last for up to 50 years—and a newly discovered metabolic pathway is key to this longevity. By Lauren J. Young Published Jul 22, 2022 2:45 PM EDT Add Popular Science (opens in a new ...

With IVF and egg-freezing techniques, women no longer need to plan their family based on their biological clock. Hence, they get to focus on the other aspects of life, and then embrace motherhood when ...

Advances in reproductive science suggest that fertility is shaped not only by the number of eggs remaining in the ovaries, but also by the biological quality and cellular health of those eggs.