This Journal feature begins with a case vignette highlighting a common clinical problem. Evidence supporting various strategies is then presented, followed by a review of formal guidelines, when they ...

There is an ongoing battle between specialists and generalists in this country. This is a battle that is most commonly seen in sports and applies to other industries. Half of the population seems to ...

Generalized pustular psoriasis (GPP) is the rarest form of psoriasis, a chronic autoimmune skin condition. Unlike other forms, GPP can be severe or even life-threatening. The disease causes flares of ...

Feeling anxious, worried, or concerned is a normal part of life. However, people with generalized anxiety disorder (GAD) worry so intensely that it interferes with their daily life. GAD is associated ...

In generalized edema, fluid collects in the interstitial tissues, either because more fluid is being secreted or because removal of the fluid is failing. The effects of gravity mean the swelling is ...

The FDA has accepted a Biologics License Application for imsidolimab to treat generalized pustular psoriasis, a rare inflammatory skin condition.