A study conducted at the University of São Paulo (USP) in Brazil reveals that tissues such as the tonsils and adenoids can ...

A review found that CD4/CD8 ratio could be used as a prognostic marker for mortality in patients with HIV, though future studies need to be done to confirm these findings. Clinical practices can ...

Infection with viruses and other rapidly replicating pathogens generates large numbers of effector CD4 T cells in secondary lymphoid sites, where they originate, and at sites of infection to which ...

A lower CD4 count is associated with a higher risk for cervical carcinoma in situ and cervical cancer in women with HIV infection.

National Institutes of Health researchers shared new details about idiopathic CD4 lymphocytopenia (ICL), a rare immune deficiency that leaves people vulnerable to infectious diseases, autoimmune ...

Checking CD4 helper T cell levels up to 4 times a year has been a mainstay of HIV/AIDS monitoring, but the value of the test has diminished as the ability to directly detect viral RNA has improved and ...

Decades after its discovery, the emerging view of idiopathic CD4 lymphocytopenia (ICL) -- popularly dubbed "AIDS without HIV" -- is that it may be more homogeneous than originally thought, despite ...

This manuscript reports an important study in which the authors apply smFRET imaging to probe HIV-1 Env conformational dynamics in the presence of antibodies. Previous implementations of smFRET ...

The rollout of vaccines against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pathogen has led to a significant reduction in coronavirus disease 2019 (COVID-19) cases, ...

In this study, we revealed the pulmonary pathogen profiles of immunosuppressed ICU patients based on CD4+T-cell counts: the severe group showed a predominance of fungal/rare infections, whereas in the ...